Getting My ceesdekker To Work
Getting My ceesdekker To Work
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Rotary motion of DNA rotors on nanopores. Top rated row: raw video with the Cy5 channel of each rotor. Center row: corresponding single-particle localization success of equally finishes on the DNA rotors. The position of the present frame is marked as orange and blue dots, along with the trajectory of the 10 frames ahead of the current body is revealed as stable lines.
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, Groningen researchers present the outcomes of their attempts to generate labs additional sustainable and provide techniques for other labs.
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on solitary molecules and metallic clusters
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent structure in 2005. (nl)
SMC complexes can pass Bodily roadblocks bigger than their ring dimensions, indicating a nontopological mechanism for DNA loop extrusion
Several connected developments adopted, exactly where our group founded different transistor variants like single-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into little evidence-of-principle Digital circuits.
Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in grey, the rim of the pore is highlighted in purple, and a 3D rendering with the motion on the DNA rod is displayed.
The rotors harness Vitality from the nanoscale water and ion circulation that is produced by a static chemical or electrochemical opportunity gradient inside the nanopore, which happen to be set up via a salt gradient or used voltage, respectively. These artificial nanoengines self-Arrange and work autonomously in physiological circumstances, suggesting solutions to constructing Vitality-transducing motors at nanoscale interfaces.
It was throughout this period that Dekker performed investigate on magnetic spin units and on sounds in superconductors and semiconductors.
Testing pseudotopological and nontopological versions for SMC-driven DNA loop extrusion from roadblock-traversal experiments
Character Physics many thanks the nameless reviewers ceesdekker for their contribution to your peer evaluation of the perform.
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2004, discovery of recent physics in translocation of DNA by way of nanopores; initial experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical properties of double-stranded RNA; and initially single-molecule review of DNA translocation by a restriction-modification enzyme.